Endocrine Abstracts

Vitamin D deficiency is more common in pregnant women than in non-pregnant women of similar age. Clinical vitamin D deficiency, associated with rickets and osteomalacia, may occur when serum 25-hydroxyvitamin D (25(OH)D) is lower than 25 nmol/l. The required serum 25(OH)D is currently set at 50 nmol/l, as lower levels are associated with lower bone mineral density, increased fracture risk and other outcomes such as lower physical performance than a vitamin D adequate state, i....

Background: Vitamin D deficiency is very common in older persons. It is not clear how serum 25-hydroxyvitamin D (25(OH)D) levels change during aging.Objective: To examine longitudinal changes in serum 25(OH)D levels in two representative cohorts of Dutch older persons during 6 and 13 years of follow-up, respectively.Methods: Data of the Longitudinal Aging Study Amsterdam (LASA) were used, an ongoing cohort study in older persons. T...